Agata Szade was awarded the grant from DKMS Foundation for the project Induction of endogenous G-CSF for mobilization of hematopoietic stem cells for transplantation.
Mobilization with recombinant G-CSF is currently the most commonly used strategy for obtaining hematopoietic stem cells (HSCs) for transplantation. We have previously shown in mice that cobalt protoporphyrin IX (CoPP) induces the mobilization of cells from the bone marrow to the blood by increasing the concentration of endogenous G-CSF. The project aim is to see if CoPP works the same way on human cells and whether the use of CoPP will enable to decrease the risk of graft vs. host disease.
The award ceremony took place during the 28th Congress of the Polish Society of Haematology and Transfusion Medicine (September, 12-14) in Lodz.
Interview with Agata on hematoonkologia.pl:
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