It might seem that this modest enzyme is the most important one. And indeed! It's quite a special one. Not only heme oxygenase-1 degrades heme to carbon monoxide, biliverdin and ferrous iron, but also affects stability of G-quadruplexes and protects cells from replication stress. You can find more in our recent paper, which is available here: https://www.sciencedirect.com/science/article/pii/S2213231724002258?via%3Dihub
Congratulation to all authors!
Commentaires